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J Exp Bot 62:869882 Price AH, Taylor A, Ripley SJ, Griffiths A, Trewavas AJ, Knight MR (1994) Oxidative signals in tobacco increase cytosolic calcium
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Known gastroparesis or severe functional dyspepsia History of pancreatitis (particularly unexplained) Active gallbladder disease or prior complications Severe IBS-C unresponsive to standard measures Significant reflux worsened by delayed emptying Planned procedures under sedation/general anesthesia (coordinate care) These arent automatic nos, but they do call for individualized riskbenefit discussions
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