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The more common experience is mild gastrointestinal adjustment, including occasional nausea, mild constipation, or reduced appetite that comes and goes
An imbalance in gut bacteria can lead to decreased GLP-1 production, contributing to increased hunger and cravings, making weight loss more challenging
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Bile acids, transformed from primary to secondary forms by bacteria including Clostridium bolteae and Bacteroides, activate TGR5 receptors and antagonize FXR signaling on L cells, both of which promote GLP-1 synthesis and release
This protective action is essential in environments where air quality is compromised
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