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Sermorelin was previously FDA-approved for diagnosing growth hormone deficiency, but it is no longer marketed for treatment, even though doctors can privately still prescribe it for other unapproved uses
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The company does conduct third-party tests for quality, purity, and consistency, but it's unclear whether they're done on raw materials, finished products, or both
We found that the combination therapy successfully targeted metabolic rewiring towards ser/gly synthesis and mitochondrial metabolism, rendering GBM cancer cells sensitive to this therapeutic strategy
Finally, we address challenges and future directions, including patient stratification by immunometabolic status, safety considerations of mitochondria-targeted treatments, and opportunities to integrate mitochondrial monitoring into perioperative care
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