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The benefits observed in studies to date depend on achieving and maintaining therapeutic dose ranges over time
careful riskbenefit assessment is warranted Those with pre-existing gallbladder disease : Rapid weight loss can precipitate gallstone formation or worsen existing biliary conditions People with severe gastrointestinal disease, including gastroparesis : GLP-1 receptor agonists slow gastric emptying, which may worsen symptoms in those with pre-existing gastric motility disorders Older adults : Age-related changes in renal and hepatic function may affect drug metabolism and increase sensitivity to side effects
Assessment of insulin sensitivity/ resistance
Comprehensive cardiovascular risk assessment should be conducted before initiating tirzepatide as part of standard care
That idea gives me hope for someone whos been in this fight for nearly two decades
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