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Research interest around TB-500 often focuses on tissue remodelling, cellular movement, and inflammatory signalling in experimental models
Auditory dysfunction and various degrees of hearing impairment are caused by qualitative or functional lesions of the auditory conduction pathways and collectively referred to as hearing loss
As a result, its difficult to draw definitive conclusions about its effectiveness
Upon injection, the PLGA matrix undergoes gradual hydrolysis, releasing the peptide over time
As such, the data suggest that incretin receptor agonists may modulate cellular pathways that initiate and amplify fibrotic remodelling in the lung
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