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Neurobiol Dis 2006
It does not establish cellular uptake, tissue distribution, duration, target engagement, or clinical effectiveness
The liposomal form protects glutathione bonds from the degradation that can occur in digestion
Their best known role is as cell housekeepers engaged in the detoxification of xenobiotics
Low GSH, neutrophil infiltration, myeloperoxidase activity and inflammation increase oxidative stress overwhelming the antioxidant defense, and hypochlorous acid mediated GSH oxidation and its attachment to proteins contribute to further GSH deficiency (114)
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