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Chronic cases may require a full 12-week cycle and occasionally a second cycle after a break to reach the target endpoint

Recent epidemiological simulations show a very bleak pattern that by the year 2040, there will be more than 3.1 million cases each year and by 2050, the number could go as high as 6 million cases annually, mainly affecting the people in Asia and Africa due to changing lifestyles and demographic patterns

In the context of weight management, these "instructions" target the root causes of weight gain, such as poor fat oxidation, insulin resistance, and declining growth factors

Usman MS, Bhatt DL, Hameed I, et al

Dias-Junior et al