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In the respiratory space, in addition to asthma, researchers and physicians are interested in seeing whether they might benefit patients with COPD
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Notably, in the active-state structure we observe a methionine-aromatic interaction between M121 3.40 , part of the PIF activation motif corresponding to residues P210 5.50 M121 3.40 S247 6.44 in CCR8, and the key toggle-switch residue W251 6.48
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