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[12] GH release stimulates protein synthesis and nitrogen retention, which is the rationale for investigating GH secretagogues in catabolic states such as post-surgical recovery, critical illness, prolonged bedrest, and age-related muscle wasting (sarcopenia)

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An older, well-documented case study described a woman who drank about 1 cup of diluted ACV daily for six years and developed dangerously low potassium and osteoporosis, highlighting how long-term, concentrated use can have real consequences