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Mitochondrial abnormalities are another hallmark of cystinosis, with studies demonstrating reduced ATP production and evidence of metabolic imbalances [144, 146, 148]
Mongioi L, Calogero AE, Vicari E, Condorelli RA, Russo GI, Privitera S, Morgia G, La Vignera S (2016) The role of carnitine in male infertility
These effects were achieved through direct inhibitory actions on prostatic GH-RH receptors, as evidenced by significant tissue-specific reductions in levels of NF-B/p50, cyclooxygenase-2, and androgen receptors, and changes in the expression of over 90 genes related to growth, inflammation, and signal transduction
C., Usui, W
Vukojevic et al., 2020)
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