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Copper binding occurs through histidine imidazole nitrogen and N-terminal amino group, forming stable 1:1 complex
He did not take GLP-1s
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When Metformin Remains a First-Line Choice Metformin remains the standard initial medication for type 2 diabetes because it is affordable, well-tolerated, has decades of safety data, and addresses insulin resistancethe root driver of many metabolic disorders
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