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As GSH: GSSG serves as an accurate representation of cellular redox status it is also valuable as a biomarker for patient classification, active monitoring of treatment and the patients physiologic response, and an easily obtained measure of immune exhaustion or oxidative burden (Rossi et al., 2006
[ref] Nitric Oxide Connection Endothelial nitric oxide is a gas produced by the endothelial cells that line blood vessels
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Slow titration lowers the acute burden
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