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(B) Dot plot displaying critical marker transcripts used to distinguish clusters
For BMI above 40, comparison between GLP-1 therapy and bariatric surgery involves weighing multiple factors including health status, personal preferences, and long-term management considerations
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In the STEP 1 trial extension, participants regained roughly two-thirds of their lost weight in the year after stopping semaglutide, with cardiometabolic improvements largely reverting toward baseline
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