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Wang C, Yuan W, Hu A, et al
Clinical trials of FDA-approved semaglutide and tirzepatide show average weight loss of 1521% of total body weight, far beyond what lifestyle changes alone typically achieve (individual results vary and are not guaranteed)
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On balance, current evidence indicates that GLP-1 agonists do not harm testosterone levels if anything, they tend to raise testosterone in overweight men by aiding weight loss and possibly through direct pituitary stimulation (higher LH)
It was now clear that GLP-1 based therapies had tremendous potential
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