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B12 supplements can interact with certain medicines, including: Chloramphenicol (Chloromycetin Sodium Succinate) Proton pump inhibitors Metformin (Glucophage, Glumetza, Riomet) Gastric acid inhibitors If youre taking any of these medications, talk to your doctor or pharmacist before starting a B12 supplement
In adults (offlabel): may support favorable changes in body composition, energy, recovery, and metabolic markers (evidence limited
Oral supplements may be suitable for some adults, while others with significant deficiency or poor absorption may need clinician-directed injections or another prescription form
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