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however, it needs building blocks for repair either from supplementation or diet
Withanolide A reverses neuronal apoptosis in CA3 region of hippocampus following hypoxic exposure and depletion of GSH Exposure to hypobaric hypoxia significantly (F (6, 36) = 11.33, p0.05) increased the number of apoptotic caspase 3 positive cells and hoescht positive cells (F (6, 36) = 21.48, p0.05) in hippocampal region compared to normoxic group
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The human brain due to the high oxygen consumption is extremely susceptible to the generation of reactive oxygen species
We propose that these changes might be involved in the disease. Oxidative stress results from the accumulation of free radicals, highly reactive molecules that can damage cells, membranes, lipids, proteins and DNA
