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Taken in conjunction with previous results, it suggests that while GLP1R and GR agonism in conjunction is able to produce large decreases in weight (Via the reduction of food intake and increased energy expenditure), but the absence of GIPR agonism produces a more unfavourable frequency of side-effects
2022;11:e79418
TABLE 2 Pharmacokinetic parameters of BPC157 in rats following intramuscular administrations of doses ranging between 5 and 120 g/kg (mean SD, n = 6)
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[15] [16] When used with insulin or sulfonylureas, dose adjustments of these medications may be needed to reduce hypoglycaemia risk
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