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Recent studies reveal its capacity to induce ferroptosis in colorectal cancer cells through ROS-dependent lipid peroxidation and downregulation of SLC7A11/GPX4 pathways, while simultaneously activating autophagy-related apoptosis via FOXQ1 inhibition [134,135,136]

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Adjuvant nivolumab in muscle-invasive urothelial carcinoma: exploratory biomarker analysis of the randomized phase 3 CheckMate 274 trial