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Retatrutide is a multi-functional peptide drug that acts as an agonist of the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors
However, it's typically mild, affects only a minority of users, and often improves as your body adjusts to both the medication and reduced calorie intake
Diabetes Complications 31 , 218222 (2017)
Moreover, every effort was made to minimise clinical doubt, by using a model of diabetes that has been extensively published and validated and by performing a series of wide-ranging sensitivity analyses that were conducted around numerous aspects of the modelling analysis, including the time horizon, treatment switching approaches, and applied reductions in HbA1c and BMI, and these did not change the conclusions of the analysis