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Missing one dose every 8 weeks (6 to 7 missed doses per year) reduces average weight loss by roughly 15% compared to perfect adherence, based on real-world data from specialty pharmacy refill records (McCall et al., Journal of Managed Care & Specialty Pharmacy , 2025)
They found widespread associations with benefits to cognitive and behavioral health, while also revealing increased risks for pancreatitis and kidney conditions, among others
This comprehensive guide aims to shed light on both methods, helping you make an informed decision tailored to your health goals