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Figure 1 The TME of osteosarcoma is characterized by a dense, mineralized extracellular matrix (ECM) and the infiltration of immunosuppressive cell populations that collectively orchestrate resistance to immunotherapy

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Beyond pancreatic -cells, GLP-1R is also found on various other cell types, such as neuronal cells, cardiovascular cells, gastrointestinal smooth muscle cells, and immune cells [10,11,12,13,14,15,16,17] (Fig

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