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Complex oscillatory waves emerging from cortical organoids model early human brain network development

& El-Sayed, M

Ubiquitin is typically conjugated to lysine residues on substrate proteins, most classically via K48 linkages, forming polyubiquitin chains that are recognized by the 26S proteasome

Research shows that IGF-1 levels are already elevated in major depressive disorder (MDD) and bipolar disorder , and adding more could worsen underlying dysregulation

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