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00:21:05 Steve Small: Right
Because appetite is suppressed, the practical answer is protein density per serving rather than larger meals: whey delivers a rapid rise in circulating amino acids (peak around 90 minutes), while casein and calcium caseinate release more slowly over several hours and support sustained satiety [1]
Comparison of mechanism, pulsatility, and research applications
The PANTHEON trial, a large double-blind RCT in GOLD defined COPD patients with severe airflow obstruction and a history of 2 COPD exacerbations in the previous year, found that NAC 600 mg BID reduced exacerbation rates in NAC group (497 acute exacerbations in 482 patients, 1.16 AcEx/pt/yr) versus placebo (641 acute exacerbations in 482 patients, 1.49 AcEx/Pt/yr), p 1 log 10 ) compared to untreated controls (67)
doi:10.1007/s00394-020-02247-8
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