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In parallel with rapid shifts in the small intestinal microbiota, impairments in the regulation of glucose homeostasis via small intestinal lipid sensing occur following just 3 days of HFD feeding 130
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PMID 7446484
In this context, a post-hoc subgroup analysis of the multicenter, randomized, double-blind, placebo-controlled VITATOPS trial (49) proposed that the small benefit of homocysteine-lowering by B vitamins might be canceled in patients treated with antiplatelet drugs (50)
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