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The novel analogs were tested for their inhibitory activity against COX-1 and COX-2 enzymes, and compound 20 (Figure 19) was further evaluated for its in vitro anti-inflammatory capabilities
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The results showed that the best EVs yield was observed in scheme 3, indicating that the compactness of the tissue would hinder the release of EVs into the supernatant, resulting in low yield of EVs
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