A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes
However, some people may experience some pain, swelling or redness at the injection site, and in much rarer cases headaches, itching or nausea
According to Harvard Health, (6) factors related to a vitamin B12 deficiency include: Limiting animal products in the diet Vitamin B12 is naturally found in meat, poultry, fish, and dairy products, so individuals that don't eat animal products can often become deficient
How Frequently Do You Typically Receive Vitamin B12 Shots
These compounds could potentially complement 5-amino-1mq in protocols focused on metabolic health