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Additionally, intestinal FXR activation leads to the upregulation of fibroblast growth factor 19 (FGF19), a key player in metabolism [63]

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In this study, SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia, we see that the SARS-CoV-2 virus inhibits the first step in mitochondrial energy production