Now, the other thing that does happen in perimenopause, menopause
Half of people taking GLP-1 medication report feeling judged or shamed for using weight-loss medication
One area that has attracted academic discussion, press coverage, and significant biotechnology/pharma R&D investment is concern about undesirable, collateral skeletal muscle mass (SMM) loss, and presumably by extension, loss of strength and function in people taking GLP-1 medications
In-vitro fibroblast assays: Pickart & Margolina (2018, Biomedicines ) and the broader fibroblast literature report working concentrations of 110 M GHK-Cu in culture medium
These VEGF-independent pathways may aid resistance to VEGF-targeted therapies, highlighting the need to identify and target alternative pro-angiogenic signals