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In these models, Dihexa administration restored performance on the Morris Water Maze (a spatial memory task) to near-baseline levels, suggesting that HGF/c-Met activation can compensate for cholinergic deficits
GLP-1 receptor agonists function by mimicking the effects of the natural hormone GLP-1, which regulates appetite, food intake, and glucose metabolism
Access this chapter Similar content being viewed by others References Abdel-Halim SM, Guenifi A, Khan A, Larsson O, Berggren PO, Ostenson CG, Efendi S (1996) Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: a defect ameliorated by cAMP
Semaglutide produces substantial weight loss , often 15-20% of body weight over 68 weeks
doi:10.1016/j.amjmed.2009.03.015 Kooy A et al (2009): Long-term effects of metformin on metabolism and microvascular and macrovascular disease in patients with type 2 diabetes mellitus
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