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These metals also interfere with the skin's natural antioxidant systems, creating a state of chronic oxidative stress that accelerates the aging process

These in vitro findings were corroborated in vivo , where CTS treatment alleviated pathological featuresincluding mucosal ulceration, inflammatory infiltration, and tumor formationin AOM/DSS-induced mice

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reported an association of Raf kinase inhibitory protein (RKIP) expression with responsiveness of GH-secreting tumors to SS analogs

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