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Common signs of B12 deficiency include fatigue, weakness, pale skin, shortness of breath, numbness or tingling in the hands and feet, difficulty maintaining balance, and cognitive issues like memory problems

Hence, although future kinetic studies might confirm a random mechanism for the rate-limiting first part of monothiol mechanism (iii) in vitro, GSH is probably the first and the non-glutathione disulfide the second substrate under physiological conditions in vivo (Fig

Expression of HNF4 at the protein and transcript levels decreases in many liver diseases (99)