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There were several factors varying between our patient and the other cases, particularly our patient also taking an SGLT2 inhibitor, but our case may suggest greater risk of EKA for a patient on synergistic regimens, Louwagie says

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A major real-world study published in early 2026 led by researchers at Johns Hopkins Bloomberg School of Public Health and analysing electronic health records from approximately 175,000 people with T1D in the US found that those taking GLP-1 drugs had a roughly 15% lower five-year risk of major cardiovascular events and a 19% lower risk of end-stage kidney disease, without any increase in hospitalisation for DKA or severe hypoglycemia

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and females: SD vs WD: p = 0.000, Cohens d = 2.590