In mice, ipamorelin increased food intake, serum leptin and relative fat mass
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Longstanding options for obesity management include diet and lifestyle modification, pharmacological therapy, and bariatric surgery
The lipid-modifying effects of GLP-1RAs are modest in comparison: the SELECT lipid analysis reported net placebo-adjusted reductions of approximately 2% in LDL-C and 15% in triglycerides [34]
Direct measurement of GFR is often considered not feasible as it requires inulin or iothalamate clearance, and therefore equations to estimate GFR are used