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Oral bioavailability of MEDI7219 tablets Oral tablet formulation Tablets contained 0.510 mg of MEDI7219, 150 mg of permeation enhancers (50 mg NaCDC [Prodotti, Basaluzzo, Italy] and 100 mg PG [Guangzhou Hanfang Pharmaceutical, Guangzhou, China]), mannitol (Roquette, Keokuk, IA, USA) as filler, crospovidone (BASF, Ludwigshafen, Germany) as disintegrant, sodium stearyl fumarate (JRS Pharma, Rosenberg, Germany) as lubricant and hydrophobic fumed silica (Evonik, Parsippany, NJ, USA) as glidant, with a total weight of 245 mg per tablet
10.1016/j.bbamcr.2012.06.019 Biochim
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