Safety, Regulation, and Quality Concerns From a regulatory perspective, AOD 9604 is not approved by the US FDA, and thus it has no approved medical indications
If your physician tells you your vitamin B12 levels are low, that means the number of red blood cells (that carry oxygen), white blood cells (that fight infections) and platelets (that help your blood clot) will be lower than normal and/or abnormal in size and function
The largest Phase 2b trial used 0.25, 0.5, and 1 mg per day for 24 weeks, but it missed its main weight-loss endpoint
Eligibility for compounded tirzepatide with B12 for weight loss is determined by a licensed healthcare provider
Production [edit] Methylcobalamin can be produced in the laboratory by reducing cyanocobalamin with sodium borohydride in alkaline solution, followed by the addition of methyl iodide