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doi: 10.1021/acs.jafc.2c01013 207 ShenL-FChenY-JLiuK-MHaddadANSSongI-WRoanH-Yet al

198 SIRT1 activation represents a potential strategy to disrupt the pathological feedback loop of microbiota imbalanceendotoxin entry into the liverinflammation activationliver damage, offering a novel entry point for systemic intervention in MASLD

It is estimated that the cultivation of 1 kg of mushrooms generates approximately 5 kg of spent mushroom substrate, which extrapolates to an annual production of around 38.3 billion kilograms of SSS [108, 118]

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For best results, use daily and apply as needed, focusing on areas prone to dryness