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Lack of clinical evidence and human trial data While the mechanisms of action of Schisandra chinensis and its lignans are well-documented, the majority of research is preclinical, with only a few human studies available [121,122,123,124]

However, the association between MTHFD2L, which can use either NAD + or NADP + for dehydrogenase activity, and tumors remains to be investigated

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When H 2 O 2 increases there are several effects on one-carbon metabolism