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doi:10.1089/ars.2012.4644, PMID: 22530666 Franco R, Panayiotidis MI, Cidlowski JA (2007) Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation
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The disruption of this endothelial-pericyte metabolic coupling restricts microvascular perfusion, intensifies vasogenic edema, facilitates leukocyte infiltration, and progressively worsens parenchymal mitochondrial stress [17, 18]
*NRV: Nutrient Reference Value for an adult
Additionally, ICH increases levels of iron-binding proteins and TF, leading to substantial Fe 3+ endocytosis into brain cells (Chaudhary et al., 2013
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