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Although we havent seen that in humans yet, it was a side effect noted in animal studies
This enhancement is demonstrable through an increase in mitochondrial DNA content, the upregulation of genes integral to mitochondrial biogenesis, and the increased expression of proteins pivotal in oxidative phosphorylation
The longest published human exposure is 12 months of sermorelin in diagnosed children, and 7 days of intravenous ipamorelin in surgical patients
This was seen in a roughly dose dependent manner but only led to 3 patients dropping out because of it
