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(PubMed) Jeppesen PB, Hoy CE, Mortensen PB

428 A meta-analysis evaluating platinum-based vs

TPSA (topological polar surface area) is one of the most commonly used molecular descriptors in medicinal chemistry for predicting properties such as membrane permeability, transporter-mediated efflux, oral absorption, and CNS penetration

Combination products containing additional brightening agents require more rigorous assessment for cumulative effects.

Moreover, a meta-analysis on diabetic patients, indicated that synbiotic supplementation markedly ameliorated FPG, insulin, HOMA-IR, and QUICKI, supporting our findings as well (81)