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Lin J, Yang T, Peng Z, Xiao H, Jiang N, Zhang L, et al
Thus these changes must come from some other effect of chromosome 21 trisomy
The company points out that D-ribose, with a short half life of 20 minutes, may accelerate the absorption of ubiquinol, which has a 6.5 hour half life
doi: 10.1038/s41380-022-01792-4 68
We prioritized genes belonging to several biological classes related to kidney function based on: missense variants (either the lead or a proxy variant, 34 genes), DEPICT gene prioritization results (156 genes), significantly colocalized eQTLs in either kidney (4 genes) or non-kidney (187 genes) tissue, or nearby Mendelian kidney-disease genes (Supplementary Tables 12, Supplementary Data 24)
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