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Common side effects and contraindications (bullet list): Mild injection-site redness, bruising Increased hunger, flushing, water retention Headache, dizziness, nausea Temporary joint discomfort Contraindications: active cancer, uncontrolled diabetes, pregnancy, certain cardiac conditions Long-Term Effects Long-term use of CJC-1295, either alone or in combination with peptides such as Ipamorelin, may cause persistent changes in hormones impacting reproductive health and aging

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Feussner A, Rolinski B, Weiss N, Deufel T, Wolfram G, Roscher AA

Importantly, GHK-Cu did not negatively impact cell proliferation or NO secretion in these macrophages, suggesting its protective effects were specific to inflammatory pathways rather than general cytotoxicity [1]

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