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46 This study indicates several confounding factors influencing HbA1c reduction: baseline HbA1c, gender, and age, and also reports that ultimate BMI reduction was significantly associated with baseline HbA1c, baseline BMI and type of GLP-1 analogue

However, how androgen signals dictate the cells from the periosteal progenitor lineage to be recruited and enriched to the injury sites of bone fracture, and whether androgen/AR signaling can activate the paracrine signalings of these cells in bone healing niches, remains to be further elucidated

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