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"The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment." Physiological reports 9.1 (2021): e14660
Rothstein JD, Van Kammen M, Levey AI, et al
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They are now commonly used when: Metformin alone is no longer enough Weight gain is contributing to worsening glucose control There is a need to minimise hypoglycaemia risk Someone has existing cardiovascular disease or multiple risk factors For many people, GLP-1 therapy can delay or reduce the need for insulin, or allow insulin doses to be kept lower and safer
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