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Potential Side Effects Reported side effects may include: Injection site pain, redness, or irritation Mild diarrhea Itching or rash Headache Dizziness Nausea Hypokalemia (low potassium)
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Thats why the FDAs own technical staff has recommended against expanded access, and the public health group Partnership for Safe Medicines calls them "popular, unproven, dangerous. As Peter Kolchinsky, managing partner of biotech investor RA Capital Management, puts it: Is the FDA going to stand on science or is it going to permit all kinds of snake oil to be readily available? The FDA meeting will last two days
Science Transl Med
Piperlongumine and some of its analogs inhibit selectively the human immunoproteasome over the constitutive proteasome
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