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Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport
The efficacy of liraglutide on weight management was subsequently surpassed by semaglutide, which, when administered weekly at a dose of 2.4 mg in obese patients without diabetes, resulted in a weight reduction of 12.4% compared to placebo in the STEP 1 study [46], and a reduction of 9.4% compared to liraglutide 3.0 mg in the STEP-8 study [47]
The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
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