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Another effect of Epithalon on the skin fibroblasts during aging is the reduction of the enzyme caspase-3 activity, which is in the pathway of apoptosis or programmed cell death
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In rats, DSIP stops somatostatin release through dopamine pathways, which could indirectly increase growth hormone (GH) (8)
The tissues were blotted on filter paper, weighed, and homogenized in 0.05 M phosphate buffer (pH7.5) using a tissue homogenizer at 40C
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