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The results of the meta-analysis for the associated biochemical parameters are presented in Supplementary Tables S1S3

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In clinical trials with participants with obesity, 5 mg, 10 mg, or 15 mg of tirzepatide once weekly provided substantial and sustained reductions in body weight over 72 weeks [22]

For most patients, these symptoms are temporary and manageable, but anything persistent or severe - such as abdominal pain, bladder issues, or constant insomnia - warrants medical review