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Gastrointestinal side effects Both phentermine and tirzepatide affect the gastrointestinal system, though through different mechanisms

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Patients taking this medication at our practice routinely tell us they no longer crave their favorite unhealthy foods

Besides, reduced appetite, anorexia and altered intestinal motility often accompany intestinal inflammation, and might be linked to EEC, since PYY, GLP-1, and CCK signal satiety and modify motility (163, 164)

However, the lack of folate in the diet, or the lack of folic acid supplementation, is directly correlated to neural tube defects occurring during fetal development