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The aqueous extract as well as hydroalcoholic extract of Curculigo orchioides were tested in diabetic rats and found to have significant hypoglycemic and anti-diabetic activities at 500 and 1000mg/kg in diabetic rats [126, 127].Researchers also reported that chlorophenol compounds that are extracted from Curculigo orchioides have inhibitory effect on alpha-glucoside and it has been found to have potent effect against diabetes milletus as well [128]
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Novo Nordisk modified the GLP-1 molecule by attaching a fatty acid chain that allows binding to albumin in your blood, protecting the medication from rapid breakdown
Drug resistance resulting from kinase dimerization is rationalized by thermodynamic factors describing allosteric inhibitor effects
Freezing can damage the peptide structure despite glycine cryoprotective properties in controlled pharmaceutical settings
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